Cancer diagnosis and treatment require careful evaluation of many factors. These include tumor type, genetic markers, possible side effects, and patient preferences. Machine learning (ML) and AI systems are being made to help doctors manage these complicated tasks. Two recent research projects stand out for what they show about how AI tools work in oncology and how patients and doctors respond to them.
At Cornell University, researchers created an AI-guided decision support system called i-SDM (interactive Shared Decision-Making). It helps older adult cancer patients and their doctors talk better about treatment options, risks, and benefits. At the same time, Harvard Medical School scientists built CHIEF (Clinical Histopathology Imaging Evaluation Foundation). This AI platform looks at cancer tissue images to diagnose cancer, predict patient survival, and suggest treatment based on molecular profiles. Both tools show different uses of AI in oncology. i-SDM focuses on supporting decisions with patient involvement. CHIEF looks at improving diagnosis and understanding genetics.
How well patients and doctors accept AI tools is very important for using AI in oncology. If people resist or doubt the tools, even the best technology might not work well. Recent studies from the US give detailed information about this issue.
The Cornell study had good results for improving talks between doctors and older adults with cancer. The i-SDM system uses machine learning and language models to show treatment information made for each patient. This includes survival rates and side effects. It helps patients be involved and helps doctors understand concerns beyond medical facts, like travel costs and easy access to treatment. For example, older patients often must think about how far they travel for cancer treatment. This can affect their choices.
Still, some patients and doctors were unsure about using AI. Two patients and one doctor in the study did not want to use the tool. They worried the AI might not know enough and could give wrong information. This shows a big challenge: not everyone feels safe relying on AI for serious choices like cancer treatment. Older adults who don’t use technology much may feel this way more.
The research listed ten things that affect treatment choices. These include survival rates, risks, treatment options, costs, and travel. With AI help, doctors could talk about treatments better and with more facts. But shared decision-making takes more time and can be hard for some patients to understand during regular clinic visits. AI tools like i-SDM try to fix these problems, but people must trust them first.
Co-author Bob Riter said shared decision-making “accurately reflects patient wishes,” especially in cases like early-stage prostate cancer where many treatment options exist. Still, the concerns about AI show that the tools need to get easier to use and that patients need better education, especially older ones.
At Harvard Medical School, the CHIEF model is for a different kind of AI use — automatic diagnosis and predicting outcomes. This tool studies images from tumor biopsies to find cancer types, guess survival chances, and find genetic mutations that affect treatment. CHIEF was almost 94% accurate in finding cancer in 19 types. It could predict survival better than other models by 8-10%.
Because it is accurate and works for many cancer kinds, CHIEF might change cancer care workflows. It can work with images from different cancer types and hospitals, showing it can fit into real clinical work. Researchers pointed out that CHIEF found new tumor features, like immune cells linked to longer survival. Pathologists had not seen these before. This shows that AI can add to clinical knowledge.
But not all doctors accept new technology fast. Even if AI helps make better diagnoses, doctors need to trust and understand its advice before using it in treatments. Lead researcher Kun-Hsing Yu said they built a “nimble, versatile ChatGPT-like AI platform” meant to be used widely in clinics.
The Cornell team is working to add a health fairness part in i-SDM. This aims to help vulnerable groups who often have more health problems and less access to technology.
Getting approval from regulators and proving clinical value are also important. Some machine learning models have gotten official approval for certain cancer uses, which helps doctors trust them more. But wide use needs ongoing teaching and proof that AI helps in real care.
For cancer clinics and medical managers, adding AI tools means fitting them into daily work smoothly. AI should not make work harder but should help make tasks easier, improve work output, and support patient care.
IT managers in cancer centers should work closely with AI suppliers to make sure systems work well with electronic health records (EHRs) and that data flows smoothly.
When AI tools give clear and useful information, patients tend to take part more in their care. This is very important in cancer treatment, which often lasts a long time and requires balancing life quality and results.
The i-SDM tool shows treatment side effects, survival chances, and other options clearly. This helps patients think carefully about their choices. Research shows that patients get better at following treatment plans when supported like this.
But how much patients get involved depends a lot on how comfortable they feel with AI and how the healthcare team explains AI advice kindly.
Research is still improving AI tools to better serve diverse patients, make them easier to use, and add more features. The CHIEF model is learning to work with rare cancers and to predict reactions to new treatments. Systems like i-SDM want to be easier for older patients who don’t use technology much.
Doctors, patients, and AI developers must keep talking to balance new ideas with practical needs.
AI offers new options for oncology clinics in the United States. It helps with diagnosis, treatment planning, patient communication, and workflow. But getting patients and doctors to accept AI is not simple, especially with older adults and in busy clinics. Medical managers should focus on training staff, informing patients, and choosing AI tools that fit well with current oncology work. Some AI companies provide services like phone automation that reduce paperwork while keeping patient support working well.
Putting money into AI solutions that deal with worries about mistaken information, fairness, and ease of use will help cancer clinics improve care quality and work efficiency.
AI can enhance communication between older adult cancer patients and their doctors by presenting treatment options based on patients’ information and preferences, thereby promoting patient engagement and compliance.
The i-SDM tool is an AI-driven decision support system that identifies treatment options and provides AI-generated information on survival rates, side effects, and high-quality support resources tailored for older adult cancer patients.
The i-SDM tool facilitates shared decision-making by providing contextual information that helps patients understand their treatment options and communicate their preferences to clinicians.
Older adults often experience difficulty in understanding complex treatment options, time constraints during clinical visits, and concern about the risks and benefits of various treatments.
Older patients consider survival rates, risks, alternative options, treatment costs, and travel distances to treatment centers, which can significantly influence their decision-making.
The feasibility study highlighted the importance of patient preferences in decision-making and identified ten key factors that older patients consider important when selecting treatment options.
The researchers are working to integrate a health equity component into the tool to ensure it addresses the diverse needs of older adult populations, particularly those from varied backgrounds.
Older adults with cancer often face unique challenges, such as comorbidities and lower technology literacy, which can complicate their medical decision-making and necessitate tailored healthcare solutions.
The rejection of the AI tool by some patients and clinicians highlighted the knowledge barriers and misinformation risks associated with AI in healthcare, emphasizing the importance of qualitative research.
The research team plans to continue improving the i-SDM tool, focusing on enhancing usability, integrating health equity measures, and refining its application to support diverse populations.