One of the biggest changes comes from using artificial intelligence (AI) in healthcare. AI is changing how hospitals and clinics work. It helps with better diagnoses, faster patient care, and can reduce costs. But to use AI well, healthcare workers need proper training. This training is not just about learning new software. It also includes understanding AI systems, situations they will face, and how to use these tools safely and correctly in real life.
A digital twin is a virtual copy of a real object or system. For example, in factories, a digital twin can be a copy of a machine used to test changes before doing them in real life. In healthcare, digital twins can be copies of a patient’s organs, whole hospital workflows, or health monitoring systems.
This technology started in the aerospace field with NASA’s Apollo missions but is now used in healthcare too. Neurosurgeons sometimes use digital twins of a patient’s brain to practice surgeries on exact digital models before the real procedure. This practice helps make surgery safer by showing how tissues might react and helping plan exact surgical paths. It helps surgeons do better work and improves patient results.
Digital twins in healthcare are not only for doctors. They also help train teams for working with AI systems—giving staff real-life practice with simulated AI responses before they use them in daily care.
AI changes how decisions and administrative work happen in healthcare places. Systems like Clinical Decision Support Systems (CDSS) use AI to give doctors and nurses data-based suggestions. Another AI part, called Natural Language Processing (NLP), helps quickly go through huge electronic health records (EHRs). Healthcare workers need hands-on training to work well with these tools.
Simulations give a safe place to practice:
Simulations can be done in virtual reality (VR), augmented reality (AR), or with digital twins to offer lifelike experiences. The University of Central Florida’s Knights Digital Twin Initiative (KDT-UCF) uses tech like holographic tables and touch feedback to recreate complex situations. These methods train healthcare workers not only to understand but also to trust AI, which helps avoid mistakes common with AI models.
Even with progress, healthcare workers still face big training problems related to AI:
KDT-UCF tries to solve these problems by giving graduate certificate programs and development grants. They focus on hands-on training with real AI and digital twin uses and support underrepresented groups to increase diversity and reach.
Some industries have shown the benefits of digital twin tech on a large scale. Healthcare leaders can learn from these examples:
These benefits could apply to hospitals. For example, hospital leaders could use digital twin models to rehearse emergency plans or test patient flow and resource changes before doing them in real life.
Digital twins also improve predictive maintenance for hospital machines. This reduces downtime. So, devices like ventilators or MRI machines will break less often and keep working when needed.
AI is growing in healthcare and is now used to automate workflows, which helps save time and reduce staff work. Simbo AI is a company that automates front desk phone services using AI. This shows how automation can improve healthcare communication.
Adding AI to workflows:
Healthcare managers in the U.S. must pick AI systems that are clear and fair. AI decisions should be easy to understand and trace by both staff and patients. Trust is key for using AI well.
In the future, U.S. healthcare providers need to match training with fast-changing AI technologies.
Important areas to work on are:
Federal grants and partnerships with industry are helping build better education programs. For example, the Department of Education supports graduate certificates in digital twin technologies, and IEEE offers training to improve skills in managing data, AI, and healthcare applications.
Healthcare administrators, practice owners, and IT leaders should consider these steps to get ready for AI-driven healthcare:
Using AI in healthcare raises real concerns about fairness, openness, and accountability. Articles in trusted journals like IISE Transactions on Healthcare Systems Engineering say AI tools must be easy to explain and trust. Training programs need to teach these ideas well so workers understand AI limits and when to rely on human judgment.
Reducing “hallucinations” (wrong AI suggestions) needs careful model checks and real-time validation, especially in clinical decision systems. Digital twins help by providing a place to test and find mistakes before AI gets used in care.
In short, new training methods using digital twins and simulations are an important step for U.S. healthcare systems using AI. They help staff get ready, reduce risks, and improve patient care. Challenges remain, such as creating new classes, combining different study fields, and building necessary tech. But research and team efforts are making steady progress.
For healthcare managers and IT leaders, investing in AI and digital twin training helps keep their facility competitive, meet new rules, and most importantly, provide safe and good patient care in an AI-supported environment.
The goal is to present cutting-edge research and innovative applications of AI to tackle current healthcare challenges, enhancing quality, efficiency, and resilience in healthcare systems.
Topics include improving clinical workflows, integrating AI with EHR systems, economic sustainability, and addressing critical systems-level challenges in Health AI.
The special issue invites interdisciplinary contributions from researchers, scientists, clinicians, and engineers in healthcare, industrial and systems engineering, and health informatics.
It addresses challenges in the adoption and implementation of Health AI, including maintaining data integrity and usability, and financial responsibilities for smart health devices and AI tools.
This section focuses on AI-driven tools that enhance clinical decision-making, predictive modeling for patient outcomes, and the application of NLP in electronic health records.
The special issue emphasizes developing decision support systems that ensure transparency, interpretability, and trustworthiness in AI applications within healthcare.
Emerging technologies include IoT and blockchain, aimed at enhancing epidemiology, health monitoring, and public health operations.
The use of digital twins, virtual/augmented reality, and AI-driven simulations to prepare the workforce for AI-integrated healthcare systems is being explored.
It discusses approaches to address data imbalance, high-dimensional processing, and the management of weakly labeled or sparse data.
Manuscript submissions are due by August 1, 2025, with expected final decisions by February 2026 and publication anticipated in May 2026.